FTDNA mtDNA FMS count milestones

Any discussions regarding mt-DNA markers, results or questions.

Posts: 61
Joined: Wed Mar 14, 2012 4:29 pm
PostPosted: Thu Apr 26, 2012 2:02 am
Hi all,

Someone started a thread on this subject on DNA-Forums and somehow I ended up continuing it. So, I note that FTDNA as of yesterday has completed 18,064 mtDNA full-sequence tests. Also, they have 141,105 "mtDNA records in the database." I had occasion to wonder recently if that number includes their "research database," which contains results from their associated scientists such as Dr. Behar.

Of those 18,064 FMS tests, 5,483 are on GenBank, either from direct submissions or as consented sequences sent in by Dr. Behar with his recent paper.

Bill Hurst

Posts: 326
Joined: Thu Mar 15, 2012 1:14 am

YDNA:
R1b-Z12*
MtDNA:
I3b (FMS)
PostPosted: Thu Apr 26, 2012 5:32 am
Bill Hurst wrote:Someone started a thread on this subject on DNA-Forums


'twas I. ;)

Thanks for the update.
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Posts: 116
Joined: Tue Mar 20, 2012 3:38 am
PostPosted: Sat Apr 28, 2012 2:31 am
Bill Hurst wrote:Hi all,
Of those 18,064 FMS tests, 5,483 are on GenBank, either from direct submissions or as consented sequences sent in by Dr. Behar with his recent paper.


I think the Behar et al paper also said that a large number of the "shared" FMS results will not be submitted to GenBank because they match either the new submission or existing GenBank entries.

There are still a large number of people who have not shared or submitted to GenBank, but this is a huge improvement.

Gail

Posts: 61
Joined: Wed Mar 14, 2012 4:29 pm
PostPosted: Sat Jul 07, 2012 12:57 pm
I see that FTDNA has, as of yesterday, 19,002 mtDNA full-sequence results. That's almost 1,000 new FMS results in less than 3 months. The total number of "mtDNA records" in their database is 146,062.

As for GenBank submissions, there have been 1,271 direct submissions by FTDNA customers. Dr. Behar submitted 4,222, as I remember, with his paper in late April. There are a few duplications, but about 35% of the full-sequence results on GenBank are from FTDNA customers. The cut-off date for Behar's submission was February, 2011, so there are lots more sequences that can be submitted.
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Posts: 103
Joined: Wed Mar 14, 2012 3:09 pm

YDNA:
R1b FGC30121+
MtDNA:
H1c3b* Helga (FGS)
PostPosted: Wed Aug 15, 2012 8:41 am
Thanks Bill

Can you please help me with this?

What timescale is a common ancestor for a FMS match?

My original report said 12 or 16 gens, but I heard it could be many more!
Eurogenes/GedMatch K36

North_Sea 19.47%
North_Atlantic 16.32%
Iberian 12.61%
Fennoscandian 11.36%
Italian 11.18%
East_Central_Euro 8.92%
Central_Euro 6.77%
French 4.67%
Eastern_Euro 3.50%
West_Med 1.39%
East_Balkan 1.34%
South_Central_Asian 1.34%

Posts: 116
Joined: Tue Mar 20, 2012 3:38 am
PostPosted: Thu Aug 16, 2012 4:55 am
Solothurn wrote:What timescale is a common ancestor for a FMS match? My original report said 12 or 16 gens, but I heard it could be many more!


Based on results in the U5 project, for U5a2a1 with an age estimate of about 6,000 years, about 10% of the people have no extra mutations, and about 10% of the people have 5 or more extra mutations. For the people with no extra mutations, an exact match could be 240 generations, assuming 25 years per generation. An exact match would be much more recent for those people with 5 extra mutations.

Given the random nature of the mutations, you need more information to make a meaniful estimate of the TMRCA, I recommend looking at the age of your lowest level subclade and then counting your extra mutations. This is really the only way to get an estimate of how recent your exact matches might be. Some people in U5a2a have 7 extra mutations, and I expect that a near match that differs by 1 or even 2 mutations could still indicate relatively recent shared ancestry for these people.

Gail

Posts: 43
Joined: Fri Apr 20, 2012 10:24 pm

MtDNA:
H24
PostPosted: Sat Aug 18, 2012 1:12 pm
GailT wrote:Based on results in the U5 project, for U5a2a1 with an age estimate of about 6,000 years, about 10% of the people have no extra mutations, and about 10% of the people have 5 or more extra mutations. For the people with no extra mutations, an exact match could be 240 generations, assuming 25 years per generation. An exact match would be much more recent for those people with 5 extra mutations.

Given the random nature of the mutations, you need more information to make a meaniful estimate of the TMRCA, I recommend looking at the age of your lowest level subclade and then counting your extra mutations. This is really the only way to get an estimate of how recent your exact matches might be. Some people in U5a2a have 7 extra mutations, and I expect that a near match that differs by 1 or even 2 mutations could still indicate relatively recent shared ancestry for these people.

Gail

Interesting stats, which point out the value of submitting to GenBank, even if you don't have a novel haplotype. This is the verbiage I include with my custom reports in such cases:

Every sequence makes a contribution to our understanding of how mtDNA has evolved. For instance, the number of sequences that maintain the ancestral haplotype of the clan mother help in calculating when she lived.

Posts: 61
Joined: Wed Mar 14, 2012 4:29 pm
PostPosted: Sun Sep 16, 2012 8:17 pm
Hi all,

On Friday, September 14, 2012, FTDNA reached another milestone of 20,213 FMS results. This time it took 6 months for 1,000 results, slowing down somewhat. But they did 218 on Friday, which may be more than all other companies together in history.

There are now 1,302 FTDNA direct submissions on GenBank. Submissions by a couple of other companies total seven, I believe.

Bill Hurst

Posts: 326
Joined: Thu Mar 15, 2012 1:14 am

YDNA:
R1b-Z12*
MtDNA:
I3b (FMS)
PostPosted: Mon Sep 17, 2012 10:04 pm
Bill Hurst wrote:Hi all,

On Friday, September 14, 2012, FTDNA reached another milestone of 20,213 FMS results. This time it took 6 months for 1,000 results, slowing down somewhat. But they did 218 on Friday, which may be more than all other companies together in history.

There are now 1,302 FTDNA direct submissions on GenBank. Submissions by a couple of other companies total seven, I believe.


More than 20,000 FMS records is a big number. It's a pity that less than 7% of them are publicly available to scientists. I wonder what could be made of access to the full 20K.
Use Profile/Edit Profile in User Control Panel to add your Y-DNA and mtDNA values.

Posts: 326
Joined: Thu Mar 15, 2012 1:14 am

YDNA:
R1b-Z12*
MtDNA:
I3b (FMS)
PostPosted: Mon Sep 17, 2012 10:05 pm
Bill Hurst wrote:Hi all,

On Friday, September 14, 2012, FTDNA reached another milestone of 20,213 FMS results. This time it took 6 months for 1,000 results, slowing down somewhat. But they did 218 on Friday, which may be more than all other companies together in history.

There are now 1,302 FTDNA direct submissions on GenBank. Submissions by a couple of other companies total seven, I believe.


Thanks for the update.

More than 20,000 FMS records is a big number. It's a pity that less than 7% of them are publicly available to scientists. I wonder what could be made of access to the full 20K.
Use Profile/Edit Profile in User Control Panel to add your Y-DNA and mtDNA values.
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