Living DNA

General discussions regarding DNA and its uses in genealogy research

Posts: 2223
Joined: Fri Mar 16, 2012 5:43 pm

MtDNA:
U5b2b
PostPosted: Sun Feb 19, 2017 9:05 pm
An interesting post from Tim Janzen about LDNA results.


"When I talked to Dave Nicholson at RootsTech he said that the primary reason that Living DNA didn’t release results for many months is because Living DNA knew the results were wrong and so they didn’t feel that they could release them. Dave said that Illumina’s reads from the GSA chip were incorrect for about 2.5% to 3% of the SNPs. Living DNA figured out that a significant percentage of the SNP results were incorrect as they were reviewing the data, but they didn’t know which SNP values were erroneous. They continued to ask Illumina about this situation and Illumina never acknowledged any errors on their part until Dave received a file from Illumina about 3 weeks ago that changed the reads for about 2.5% to 3% of the SNPs. Hopefully Illumina now has the reads correct for the GSA chip which will hopefully allow Living DNA to generate results faster than it has been able to generate them during the past 4 months. It seems clear from CeCe’s results and from the results of others who have tested with Living DNA that Living DNA is overestimating the percentage of DNA from the British Isles for people who have ancestry from continental Europe. As Living DNA gets more data from people who have ancestry in continental Europe they will hopefully be able to improve these estimates. It can’t be emphasized enough that doing fine scale ethnicity estimates for people with European ancestry is extremely difficult for companies to do with a high level of accuracy. Finnish and Ashkenazi Jewish DNA is the easiest for companies to tease out."

Sincerely,

Tim Janzen

Posts: 2223
Joined: Fri Mar 16, 2012 5:43 pm

MtDNA:
U5b2b
PostPosted: Tue Feb 21, 2017 8:25 am
The Living DNA company has stated that they will accept autosomal transfers from other companies this year. I hope to to transfer some FF results as long as the price is right. All my known ancestors come from a 10 mile radius of my home and I look forward to their interpretation of my dna results.

Posts: 2223
Joined: Fri Mar 16, 2012 5:43 pm

MtDNA:
U5b2b
PostPosted: Mon Feb 27, 2017 9:04 pm
Dr Iain McDonald
"The two pieces of relevant jargon are the most recent common ancestor, but applied to the whole (autosomal) population rather than just the Y-DNA line, and the identical ancestors point.
https://en.wikipedia.org/wiki/Identical_ancestors_point

It has relevance in autosomal population studies because the populations you are comparing to should be defined by the following temporal points: they must have occurred after the IAP for the global or continental population, but before the IAP of the specific population in question. Hence, if the terms "metal age invaders", "neolithic farmers", etc., are useful separators autosomal inheritance if they lie between the autosomal MRCA and the IAP for western Europe.

Even in very isolated communities (e.g. St. Kilda), the autosomal MRCA can be very recently shared with other locations. It only takes one person to be shipwrecked there to introduce a much more recent connection to the entire rest of the world, and increasingly we are finding that these communities are not as genetically isolated as we have previously thought."

Posts: 2223
Joined: Fri Mar 16, 2012 5:43 pm

MtDNA:
U5b2b
PostPosted: Fri Jun 16, 2017 7:21 am
I will buy this test at some point in time but the major gripe for me is the amount of time they take to process the results. Also,they stated that it will take two years for them to get a handle on the Irish genome. Anyone that has taken this test and the FF test should upload their results to GEDmatch to see if they produce different results in the calculators. They use a mostly different set of SNPs to the FF test, around 500,000 or more.



This was posted on the U106 forum.
"The LivingDNA autosomal raw data files are in a slightly different format from the FTDNA Family Finder raw data files, but the same type of information is delivered: the rs number for the SNP, the chromosome where the SNP is found, the position of the SNP on the chromosome, and the allele values. FTDNA and Living DNA are both using Illumina chips. FTDNA is using the Omni Express chip at this point and Living DNA is using the new Global SNP Array chip. See https://www.illumina.com/company/news-c ... id=2178011. There is relatively little overlap between Family Finder data and the Living DNA autosomal data. There are only 161,862 SNPs that are found in both datasets. See https://isogg.org/wiki/Autosomal_SNP_comparison_chart for more background. 23anMe has previously said that they will be moving to the GSA chip at some point in the future."

Posts: 2223
Joined: Fri Mar 16, 2012 5:43 pm

MtDNA:
U5b2b
PostPosted: Tue Nov 07, 2017 9:31 am
My Living Dna results with all my known ancestors were born in Ireland. I now have over one million autosomal snps between my FTDNA and Living Dna files, most of which there is no info on the internet about. It is obvious that Living Dna's Irish project is not going well at present or else they would have linked me to the Irish regions specified in their project.

https://www.livingdna.com/en-eu/one-fam ... ch/ireland

Europe96.7%
Great Britain and Ireland93.8%
Southwest Scotland and Northern Ireland34.4%
Northwest Scotland26.8%
Ireland8.2%
East Anglia5.9%
Cornwall4.8%
Orkney2.1%
South Wales1.6%
Great Britain and Ireland (unassigned)10.1%
Europe (unassigned)2.8%
World (unassigned)3.3%
Last edited by dartraighe on Mon Dec 18, 2017 11:48 am, edited 1 time in total.

Posts: 2223
Joined: Fri Mar 16, 2012 5:43 pm

MtDNA:
U5b2b
PostPosted: Thu Dec 14, 2017 11:38 am
http://thednageek.com/whats-coming-down ... iving-dna/

Furthering Your Research With Living DNA
Katie Welka, Product Specialist at Living DNA

"Living DNA is the newest player in our market, and their presentation was the first of the five companies in attendance at the conference. They boast the greatest number of world regions (80) in their admixture report. However, a disproportionate number of them are from the U.K., skewing the ethnicity estimates for those of us with ancestry from elsewhere in Western Europe. To correct for that problem, Living DNA is actively pursuing two regional projects: one in Germany and one in Ireland. These two projects will allow Living DNA to provide better regional breakdowns within those two countries.

Additional refinements to their ethnicity estimates will result from their One Family One World project, which combines transfers of raw data from other companies with their own database of tested customers to expand their reference populations. Associated with their One Family One World project, Living DNA offers an educational program that integrates DNA results with cultural awareness to improve cross-cultural empathy and understanding.

Living DNA does not currently offer relative matching. That feature will be rolled out in a private beta test soon. Paying customers are expected to receive the matching feature early in 2018, with transfer customers gaining access in mid-2018. Initially, matching will be autosomal only, although Living DNA is considering yDNA and mtDNA matching at a later date. Katie Welka did not say how large their database is at the moment.

Hardcore genetic genealogists will be pleased to hear that Living DNA has a chromosome browser in the works. Not only that, it will include regional painting, so you can see which segments of DNA you inherited from which regions of the world. I am very excited about that!

Finally, the company is working to incorporate family trees into their system. They have not yet decided whether this will take the form of links to family trees hosted elsewhere on the internet or trees that are integrated within their system."

Posts: 2223
Joined: Fri Mar 16, 2012 5:43 pm

MtDNA:
U5b2b
PostPosted: Sun Dec 17, 2017 6:26 pm
Living dna.com
"Technical Note"
"We are currently expanding our Irish samples in our panel to fully recover Irish ancestry, although people with grandparents from Ireland are nearly always assigned at least some Irish ancestry. This is going to be improved greatly, with the expansion of our Irish dataset.

If you have Irish ancestry that you didn’t expect: This is probably real Celtic ancestry, but may reflect Scottish ancestry instead. One of our regional groups spans the Irish sea between Northern Ireland and South West Scotland, reflecting close genetic similarity between Scotland and Ireland.

If you have Irish ancestry but it is not inferred as strongly as expected: Unfortunately, due to the current limited number of Irish samples, we currently see many Irish people as a mixture of Ireland, Northern Ireland and South West Scotland, and North West Scotland. Many people will receive some English ancestry as well. This is “real” in the sense that the small Irish sample means that our method looks very far back into the past, perhaps 2000 years, and hence this accurately represents where your ancestors from that time have now spread out to live."

Posts: 2223
Joined: Fri Mar 16, 2012 5:43 pm

MtDNA:
U5b2b
PostPosted: Mon Jan 01, 2018 10:22 pm
I believe that the dna of the doggerland people can be found in the Mesolithic samples from the east coast of Britain, north west France, Begium and the Netherlands. The North Sea component in the Eurogenes K15 might be linked to Doggerland due to the fact that Loschbour man had it. U5b and I2b should be among the female and YDNA lines of the Doggerland peoples.

In the past, I thought that U106 might be linked to Doggerland but U106 is estimated to be only 5,000 years old and Doggerland disappeared 7,000 ybp.


Eurogenes EUtest V2 K15 Oracle results:
Kit F999918 Loschbour 8,000 ybp Luxembourg.
Admix Results (sorted):
# Population Percent
1 North_Sea 34.51
2 Baltic 33.51
3 Atlantic 23.86
4 Eastern_Euro 7.33
5 Oceanian 0.8


http://www.strangehistory.net/2014/05/11/18787/
In Search of Doggerbank: The Island of the Damned

Posts: 2223
Joined: Fri Mar 16, 2012 5:43 pm

MtDNA:
U5b2b
PostPosted: Wed Mar 21, 2018 8:20 am
https://www.livingdna.com/de/blog/307/f ... ion-method

Family Networks: a new DNA-driven matching system and family tree reconstruction method
"On the 28 February, Living DNA announced Family Networks — a new DNA-driven matching system and family tree reconstruction method based solely on users’ DNA, gender, and age.
Unlike competing organizations, Family Networks will provide the most precise matching service on the market by analysing a user's unique motherline and fatherline DNA data (mtDNA and YDNA), on top of the family ancestry line (autosomal).

Living DNA’s matching tool will take the guesswork out of relationships by predicting relationships with more specificity than any other competitor. With input as minimal as DNA and birthdate, Living DNA can build a family tree that shows where matches fit in.

The unique computation this feature provides gives customers, even those who upload from other DNA testing sites, a level of relationship prediction and specificity beyond anything currently on the market.

Where other offerings rely solely on time-consuming and often error-prone user research, Living DNA’s tools process users’ DNA to identify relatives and define relationships deeper back in time.

“With Family Networks, Living DNA not only predict how users are related to direct matches, but can also infer through DNA up to 13 generations back to connect matches with whom they share no DNA with today,” said Living DNA co-founder and Managing Director David Nicholson."


Also, 16.2% of my dna can not be linked to any population which makes me unique.
Britain and Ireland (unassigned) 10.1%
Europe (unassigned) 2.8%
World (unassigned) 3.3%

Posts: 2223
Joined: Fri Mar 16, 2012 5:43 pm

MtDNA:
U5b2b
PostPosted: Mon Aug 06, 2018 8:03 pm
"We’re really excited to give you a little update on our new Family networks feature.

From August we will be opening up Family Networks to our first pioneering group of Beta testers.

We will then be inviting further carefully selected groups to join the testing. This means we can take our valuable customer feedback to develop and improve our service before a wider public release.

We will be back in touch with you soon with additional updates.

Best wishes,
Living DNA customer service."

I got this email today and I am looking forward to the results. I joined Britains Living Dna for YDNA matches and I would be more interested in those than the autosomal cousins. There has to be 10 million U106 in Britain and I was hoping that I would find some YDNA matches in their database. They do not seem to be too interested in the YDNA lines.
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