Big Y, what next?

General discussions regarding DNA and its uses in genealogy research

Posts: 2154
Joined: Fri Mar 16, 2012 5:43 pm

MtDNA:
U5b2b
PostPosted: Fri Jun 02, 2017 11:11 am
Big Y is evidently on sale temporarily, $150 off, with discount code RAMBigY2017.
Last edited by dartraighe on Sun Jun 18, 2017 5:41 am, edited 1 time in total.

Posts: 2154
Joined: Fri Mar 16, 2012 5:43 pm

MtDNA:
U5b2b
PostPosted: Sat Jun 10, 2017 3:39 pm
A lot of testers must have taken advantage of this recent Big Y sale offer from FTDNA.

From FTDNA
The coupon code has reached its maximum number of uses and is not valid at this time.
Best,
Thomas H
Information Specialist

Posts: 2154
Joined: Fri Mar 16, 2012 5:43 pm

MtDNA:
U5b2b
PostPosted: Fri Jun 16, 2017 8:48 pm
The analysis of my son's BAM file is complete at Yfull. He has only 356 YSTRs and I have a result for 449. We match on all but five of the YSTRs. My son's dna sample did not produce as good results as mine. My son had only a 12 marker Y test at FTDNA when I ordered the test. He had a result for 58 of the 67 YSTR markers and 89 of 111 YSTRs markers tested by FTDNA. All were exact matches to my FTDNA haplotype.

We match on all YSNPs. We have 34 YSNPs under the terminal YSNP status that we had before the Big Y tests.

My son's YSTR results
STRs (all): 500
Reliable alleles: 356 (71.20%)
Uncertain alleles: 34 (6.80%)
N/A: 110 (22.00%)

My YSTR results.
STRs (all): 500
Reliable alleles: 449 (89.80%)
Uncertain alleles: 7 (1.40%)
N/A: 44 (8.80%)

Some of the projects have more up to date subclade Y trees but Yfull has the best and most up to date haplogroups Y-tree. Yfull has also some decent features and their analysis of the YDNA BAM files is top of the range. This has been the best value for money that I have spent so far.

Posts: 2154
Joined: Fri Mar 16, 2012 5:43 pm

MtDNA:
U5b2b
PostPosted: Wed Mar 21, 2018 8:30 pm
Gioiello
I have bought the ancestry dna test because they have 7 million testers in their database. I am hoping to find surname autosomal dna matches. And I will be asking those matches to take a Y test to determine if we are related through the Y line. A surname tester does not need to take an expensive 67 marker YSTR test nor a YSNP pack test. I can identify my own surname Y line with just one SNP that will cost a tester only $18. I am able to do this due to fact that I took the Big Y test and I have two good Big Y matches who have broken down my 32 YSNP block.

Posts: 2154
Joined: Fri Mar 16, 2012 5:43 pm

MtDNA:
U5b2b
PostPosted: Fri Apr 13, 2018 5:09 am
FTDNA is giving all Big Y testers 500 YSTRs for free. I am in batch 645 for Y500. FTDNA will have to adjust the privacy settings in the projects or all of our 500 YSTRs will be shown. I don't think that a lot of testers will be comfortable with that.

Y500 will not help U106 testers who do not have 67 marker matches. U106 testers need the 67 marker matches because the 66 marker (DYS492)is the important one. A 12 value at this marker could mean the match belongs to P312 90% of the time. YSNP tests trump YSTR tests. I have lots of 25 marker matches since January 1st and all are M269 predicted.

Posts: 2154
Joined: Fri Mar 16, 2012 5:43 pm

MtDNA:
U5b2b
PostPosted: Fri Apr 20, 2018 12:49 pm
FTDNA posted my Y500 YSTR results today. I have 450 YSTRs from my Big Y test because I already had 111. My son who had only 12 marker test is missing those from 12-111 from his Y500 so I would still have to pay for his 12-111 markers if I wanted to. I don't need to. Already I have observed that Yfull has more YSTR info than FTDNA. My closest YSNP match at Yfull has a difference of 46 out of 484 YSTRs compared. I don't see anything to get excited about the Y500 YSTR info yet. Most of the 112 -561 markers are stable markers.

YSNP tests are more accurate and FTDNA should have concentrated on improving the coverage of the Big Y test to give testers more YSNPs. And the price of the Big Y has gone up even in the sale.

Posts: 2154
Joined: Fri Mar 16, 2012 5:43 pm

MtDNA:
U5b2b
PostPosted: Sat Apr 21, 2018 8:13 am
I can find only 5 differences in YSTR values between my nearest YSNP match and me in the 450 YSTRs that FTDNA reported in the Y500. That suggests that the YSTR values in the Y500 will not be very useful in the long run. In other words a waste of time and money in my view.


The 111 markers that FTDNA chose initially for YSTR tests are the most ancestry informative markers and we can see the reason, now that they have published our results for 561 YSTR markers. YSTRs are the past, YSNP tests are the future. These five YSTR markers FTY214 ,FTY285, DYS523, FTY1016, FTY800, are the only differences I have out of 450 new YSTR markers at FTDNA with my closest match at 67 markers.

I have learned more from 32 quality YSNPs than 561 YSTR markers.

Posts: 2154
Joined: Fri Mar 16, 2012 5:43 pm

MtDNA:
U5b2b
PostPosted: Sun Apr 22, 2018 10:40 am
I think that most testers would prefer to know about their most recent YSNPs. FTDNA's threshold of 30 YSNP's for Big Y tester, 15 each of their most recent YSNPs, is the best way to go. When a tester has his Big Y results he can create a YSNP panel with his most recent YSNPs at YSEQ. YSEQ is the best price per YSNP company and the only company to facilitate this venture.

https://www.yseq.net/product_info.php?p ... b49ed90fd8

Finding autosomal matches at ancestry with the same surname and asking them to take a YDNA test to determine if one is related through the Y-line could be the way to go for some testers with no close YDNA matches at FTDNA. Ancestry boasts seven million autosomal dna testers. Ancestry also has a lot of surname trees with links to the regions of a lot FTDNA testers.

FTDNA did not do the right thing about Big Y tests. The price needs to come down to encourage testers who already have taken a YSTR test. I have a lot of 25 marker matches since the 1st January who are have tested to 37 markers but whose status is M269. All of these are Neolithic dna matches. Finding a way to get them to test for the most recent YDNA status should be FTDNA's main goal. A more expensive Y500 is not the way to go.

Posts: 2154
Joined: Fri Mar 16, 2012 5:43 pm

MtDNA:
U5b2b
PostPosted: Tue Apr 24, 2018 6:17 pm
I opened the Y500 page at FTDNA, copied and pasted the markers into excel and now I can make sense of them. When I downloaded the Y500 csv file it was rubbish. Also, FTDNA loaded all of my most recent YSNPs into the advanced YSTR marker page.


https://linealarboretum.blogspot.ie/201 ... value.html

"As Kelly Wheaton astutely added on her All Genetic Genealogy Facebook group, “The point that needs underscoring is that STRS change back and forth so their predictive value is less than SNPS that you either have them (and so do all your Y line descendants) or you don't. They are definite and predictive and now with Next Gen sequencing they are useful in a genealogical time frame. Sometimes STRS are helpful but they can also be misleading and have you barking up the wrong tree.”

Posts: 2154
Joined: Fri Mar 16, 2012 5:43 pm

MtDNA:
U5b2b
PostPosted: Tue May 08, 2018 6:51 pm
I haven't been able to gain access to the ysearch site and other posters are complaining about it also, so I deleted all my records there.


FTDNA's info for YSTR matches is hogwash. https://www.familytreedna.com/faq-markers.aspx

I have lots of 25 marker matches since the 1st January and they are all Neolithic matches except for one who is BA match. YSTR 25 and 37 marker tests will not help a tester to determine the relationship with another match. The tester will need YSNP tests and that is the only sure way for testers with the same surname. All those testers who bought YSTR tests recently just wasted their money. NGS testing is the only way forward for all those interested in YDNA tests.

I have written to some of these 25 marker matches with no replies.
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