From Ian Logan’s checker


Posts: 2311
Joined: Sun Mar 18, 2012 7:08 am
Location: Pisa (Italy)
YDNA:
R- Z2110 (KV7Y2)
MtDNA:
K1a1b1e/HQ176413
PostPosted: Fri Dec 22, 2017 5:29 pm
These two interesting mHG K1a1b1 from Northern Africa (Font-Porterias,N., Sole-Morata,N., Serra-Vidal,G., Bekada,A., Fadhlaoui-Zid,K., Zalloua,P., Calafell,F. and Comas,D.'The genetic landscape of Mediterranean North African populations through complete mtDNAs')

MG182034 Font-Porterias Haplogroup K1a1b1 17-DEC-2017
A73G C114T T152C A263G C497T G709A A750G T1189C A1438G A1811G
A2706G A3480G A4769G G6261A C7028T A7158G A8860G G9055A T9698C A10398G
A10550G T11299C A11467G A11470G G11719A G11914A A12308G G12372A C14167T
C14766T T14798C A15326G A15924G T16093C T16224C C16234T A16269G T16311C T16519C

MG182035 Font-Porterias Haplogroup K1a1b1 17-DEC-2017
A73G C114T T152C A263G C497T G709A A750G T1189C A1438G A1811G
A2706G A3480G A4769G G6261A C7028T A7158G A8860G G9055A T9698C A10398G
A10550G T11299C A11467G A11470G G11719A G11914A A12308G G12372A C14167T
C14766T T14798C A15326G A15924G T16093C T16224C C16234T A16269G T16311C T16519C
are important for understanding the origin of the Ashkenazic hg. K1a1bia, because they have two mutations (C114T and C16234T) which are at the origin of the K1a1b1a subclade.
An intermediate haplogroup is this
DQ301798 Behar K1a1b1a 20-JUN-2007
A73G C114T A263G 315.1C C497T A750G T1189C A1438G A1811G
A2706G A3480G A4769G C7028T A8860G G9055A T9698C A10398G
A10550G A10978G T11299C A11467G A11470G G11719A C11765A G11914A A12308G G12372A C14167T C14766T T14798C A15326G A15924G T16224C C16234T T16311C T16519C
(and we don’t understand why Ian Logan puts it twice in his checker)
with the mutation A10978G. It was “Submitted (22-NOV-2005) Bruce Rappaport Faculty of Medicine and Research Institute, Technion and Rambam Medical Center, Bat Galim, Efron 9 st, Haifa 31096, Israel”, but, even though it could belong to a Jewish woman, we don’t know its origin, being it unique whereas K1a1b1a multiplied in millions of samples.
At last we have the true K1a1b1a with the mutation T12954C.
Costa et al. 2013 wrote: “The origins of Ashkenazi Jews remain highly controversial. Like Judaism, mitochondrial DNA is passed along the maternal line. Its variation in the Ashkenazim is highly distinctive, with four major and numerous minor founders. However, due to their rarity in the general population, these founders have been difficult to trace to a source. Here we show that all four major founders, B40% of Ashkenazi mtDNA variation, have ancestry in prehistoric Europe, rather than the Near East or Caucasus. Furthermore, most of the remaining minor founders share a similar deep European ancestry. Thus the great majority of Ashkenazi maternal lineages were not brought from the Levant, as commonly supposed, nor recruited in the Caucasus, as sometimes suggested, but assimilated within Europe. These results point to a significant role for the conversion of women in the formation of Ashkenazi communities, and provide the foundation for a detailed reconstruction of Ashkenazi genealogical history”.

Posts: 2311
Joined: Sun Mar 18, 2012 7:08 am
Location: Pisa (Italy)
YDNA:
R- Z2110 (KV7Y2)
MtDNA:
K1a1b1e/HQ176413
PostPosted: Sun Dec 24, 2017 1:53 pm
I thank Ian Logan for having put away the double sample I spoke above.

My friend Marco Grassi got the FMS of a friend of his:

182T 263G 315.1C 750G 1438G 1719A 2851G 4769G 4793G 8860G 15326G 16519C

An H7a, but how is it possible that the mutation A2851G is found pretty always in hg H (36 samples out of 42: H1 1, H1c 2, H1h 2, H3 23, H5a 7, H11a 1, and only 6 samples all the other hgs: HV1a 1, J1c 2, G2a 1, M49e 2)? And now this H7a. We have to think that the mutation was in heteroplasmy in H* and passed and fixed only on some hgs. Of course I should do an analysis, but, seen also this sample from Fraumene et al. 2006,
11. DQ523661(Sardinia) Fraumene H3 03-OCT-2006
A263G A750G A1313G A1438G A2851G A4769G T6776C A8860G A11200G A15326G T16519C
and this
34. KM252736(Italy) Bodner H3 21-OCT-2014
A263G 315.1C A750G A1438G A2851G A4769G T6776C A8860G A11200G T15115G A15326G T16519C
I have the suspect that that H* was in Italy/Sardinia, where Hg H (and many others) may have had their origin.

Posts: 2311
Joined: Sun Mar 18, 2012 7:08 am
Location: Pisa (Italy)
YDNA:
R- Z2110 (KV7Y2)
MtDNA:
K1a1b1e/HQ176413
PostPosted: Sun Dec 24, 2017 5:08 pm
This would disprove what Olivieri et al said, that the migration to Sardinia happened from Western Mediterranean source rather that the continental Italy: “As shown in figure 2, the ages of H1 and H3 leave open the possibility that both were also present in Sardinia prior to the Neolithic. Notably, the frequency of H3 in Sardinia (18.4%) is the highest reported till now, and haplogroup H3 harbors a very peculiar geographical distribution. The highest frequencies are in western Mediterranean (Sardinians, Basques and other Iberians), with a sharp decrease towards Central and Eastern Europe and only very few occurrences in the Near East (fig. 4; supplementary table S9, Supplementary Material online), which founder analyses explain as recent incursions. Given that the population size trends for the Sardinian H3 mtDNAs indicate an expansion beginning between 9.0 and 10.5 Kya (fig. 4), it is tempting to link such an expansion to a pre-Neolithic arrival and diffusion of H3 on the island, most likely from a Western Mediterranean source, as previously suggested (Achilli et al. 2004; Torroni et al. 2006; Soares et al. 2010), possibly the same ancestral source of the ancestors of U5b1i1 and Y-chromosome haplogroup I2a1a1-M26 (Francalacci et al. 2015)”.

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